kasabach-Merritt syndrome consists of thrombocytopenia, icroangiopathic hemolytic anemia, and an acute or chronic consumptive coagulopathy in association with a rapidly enlrging hemangioma. Most vascular tumors causing kasabach-Merritt syndrome
are
benign but the associated coagulopathy may be life-threatening.
Our patient, a 30-day-old female infant, was admitted after an increase in the. size of a hemangioma present since birth on the right leg with extension to the lower abdomen and left inguinal area. Her hemoglobin count fell to 7.1g/dl, platilet
count
was 26,000/μl, prothrombin time was 26 seconds, and hypofibrinogenemia developed. The patient was treated with transfusions of platelets, fresh frozen plasma and red cells and prednisolone for 2 weeks without improvement. We started interferon
alfa-2a
therapy Over the past 6 months, the hemangioma progressively diminished in size without any serious complication. (Kor J Dermatol 1995;33(2) : 363~368)
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